O-304 (ATX-304) 100mg x60 Capsules
fat loss
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Buy O-304 (ATX-304) 100mg x60 Capsules

Pan-AMPK activator with GLP-1 synergy — NASH, diabetes, and fat loss in one compound

Pan-AMPK activationEndogenous GLP-1 stimulationNASH regression

Who This Is For

Users with metabolic syndrome, insulin resistance, or NASH who want a single oral compound addressing multiple aspects of metabolic dysfunction.

Overview & Benefits

O-304 (now ATX-304) activates all AMPK complexes — a broader activation than AICAR — producing insulin sensitization, fat oxidation, hepatic fat reduction, and gut hormone secretion including GLP-1 and PYY. Phase 2 data in type 2 diabetes showed significant glucose lowering, weight loss, and NASH biomarker improvement. What distinguishes O-304 is the gut hormone effect: by stimulating endogenous GLP-1 release, it adds appetite suppression on top of the metabolic AMPK effects. This makes it a genuinely multi-mechanism compound for metabolic syndrome — addressing insulin resistance, hepatic fat, body weight, and appetite through different but synergistic pathways.

Key Benefits

  • Pan-AMPK activation — broader than AICAR, affecting all AMPK complexes
  • Stimulates endogenous GLP-1 and PYY release for appetite suppression
  • NASH regression in Phase 2 — significant hepatic fat reduction
  • Insulin sensitization and glucose lowering in diabetic subjects
  • Multi-mechanism: metabolic + appetite via endogenous gut hormone stimulation

Protocols & Dosing

Daily Metabolic Protocol

Once or twice daily with meals
100mg oral capsule

Take with food to minimize GI effects. Run 8–12 week cycles. Monitor fasting glucose and liver enzymes.

Stack With These Peptides

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AICAR 50mg

AICAR 50mg

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O-304 (ATX-304) 100mg x60 Capsules

Buy O-304 (ATX-304) 100mg x60 Capsules

$119.99

Buy Now — $119.99Buy at Phiogen

Research-grade · COA verified · Phiogen

Categoryfat loss
Typeoral
Quality Rating★★★☆☆
VendorPhiogen

O-304 (ATX-304) 100mg x60 Capsules

$119.99

Buy Now